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β-glycosidases belong to the Glycosyl Hydrolase Family 1 <http://afmb.cnrs-mrs.fr/CAZY/fam/GH1.html>. They catalyze the hydrolysis of the glycosidic bond between the anomeric carbon and the glycosidic oxygen by a mechanism in which the anomeric conformation of the glycose is retained.


(Click here for a larger version.)

β-glycosidases are involved in diverse aspects of plant physiology including lignin biosynthesis, chemical defense against pathogens and herbivores, and growth and development. In the Cyanogenic Glucoside & Molecular Evolution research group we focus on β-glycosidases that catalyze the bio-activation of phytoanticipins with emphasis on cyanogenic glycosides.

Our FASTA files, used in creating our BLAST databases, multiple sequence alignments, and phylogenetic trees, are now available for download.


• Click here for the Lotus japonicus BGLU protein sequence file.
• Click here for the Lotus japonicus deduced cDNA sequence file.
• Click here for a protein sequence file of BGLUs from multiple organisms, collectively used in producing phylogenetic trees for Vinther Morant et al. Plant Physiol 2008 and Vinther Morant et al. Phytochem 2008.

All phylogenetic trees were made with MEGA 3.1 (1000 boostrap trials).
A phylogenetic tree containing plant β-glycosidase family members.

Logos were made using weblogo.berkeley.edu.
A logo of conserved regions of plant beta-glycosidases from the tree and alignment above.
A logo of conserved regions of Arabidopsis beta-glycosidases from the tree and alignment above.

The BGLU image shown here and on the frontpage for the site is a predicted tertiary structure of a putative cyanogenic beta-glucosidase from Oryza sativa. Please see our gallery for more information on predicted tertiary structures, and in particular this one.